PDF in Cardiac Magnetic Resonance Imaging
The Canadian Arrhythmia Network (CANet) in association with the University of Western Ontario/Lawson Health Research Institute and the Ottawa Hospital Research Institute/Ottawa Heart Institute are seeking a Post-Doctoral Fellow (PDF) with a Ph.D. in the area of cardiac MRI. The successful candidate will report to Dr Frank Prato, Lawson Imaging Program Leader (www.lawsonimaging.ca) and Dr Rebecca Thornhill, Investigator at the Ottawa Hospital Research Institute (www.ohri.ca).
The project goal is to optimize left atrial MRI to guide therapy for atrial fibrillation. Atrial fibrillation is a major cause of stroke and heart failure. Expensive and invasive therapies such as RF ablation often fail even after repeated application. Currently the MRI literature is controversial as to the demonstrated impact that MRI could have. This is, in part, due to a lack of a systematic evaluation of cardiac MRI protocols and the ability to compare in vivo imaging of the left atrium to the “truth,” i.e. histopathology.
This dedicated Post-Doc will, for the first time in the world, have access to in vivo, in situ and ex vivo cardiac/LA images (obtained in a pre-clinical model of atrial fibrillation). The post-doc will also have access to histopathology and endocardial electrical impedance mapping data, which will be essential for the validation of cardiac MRI data. The position is currently funded for two years with the potential for a third year wherein, depending on the outcome, the methodology would be translated to humans.
· Ph.D. in medical imaging, biophysics, bioengineering or related field
· Ability to apply warping/non-linear registration algorithms
· Familiarity with 3-D slicer, ITK/VTK, or equivalent software
· Proven track record in participation in team research
· Willing to travel between Ottawa and London
· Proven written and oral communication skills
Preferred Additional Requirements
· Familiarity with Siemens 1.5 and 3.0 T MRI systems
· Proven ability to design and understand cardiac MRI pulse sequences
· In depth understanding of cardiac anatomy and physiology
· Experience with cardiac histology
· Experience with hybrid PET/MRI
· Experience with cardiac PET
This position will remain open until filled