Victoria Research Laboratories

Lawson Imaging is part of the Lawson Health Research Institute (Lawson), which is the research arm of London Health Sciences Centre and St. Joseph's Health Care, London. Their research facilities are at two sites, St. Joseph's Hospital and at Victoria Research Laboratories at the Victoria Hospital. The equipment at Victoria Research Laboratories includes: 

Victoria Research Laboratories

Medicinal Chemistry Laboratory used for the design and synthesis of receptor-targeting chemical entities

  • Automated solid-phase synthesis, purification and characterization of imaging probes

Radiochemistry Laboratory used in the preparation of novel molecular imaging probes (Spring 09)

  • Radiolabelling of small molecules, peptides and larger biomolecules for SPECT and PET imaging in humans and small animals

Ultrasound Biomicroscope (VisualSonics Vevo 770) for non-invasive, accurate detection and assessment of the growth and treatment of primary and metastatic tumours in animal models

GE SPECT/CT for small animal imaging (in Animal Care Facility)

Olympus FluoViewTM FV1000 Confocal Imaging System built on the IX81 Motorized Inverted System Microscope (IX2 Series) platform

  • Imaging laser lines: 405/458/488/515/559/635 nm. Objectives: 10X, 20X, 40, 60X oil, 100X oil. Epifluorescence and DIC (Nomarski) illumination. Filter sets for DAPI, FITC, CFP and Texas Red are available for visual inspection of the samples
  • Support infrastructure for live imaging: Weatherstation for maintaining desired CO2 level and temperature setting during live imaging; drug perfusion system with perfusion chambers for cultured cells and embryos; water bath, cell-culture incubator and vortex
  • Image analysis workstation: A PC with software for analysis of confocal datasets is available in our facility. It is equipped with 2 x Dell Ultrasharp 24" wide flat panel monitors, and the following softwares: Image-Pro Analyzer (version 6.2, Media Cybernetics) and FV 10-ASW 1.6 (FluoView 1000 software, Olympus corporation)

Multi-channel near infrared (NIR) intravital spinning disk confocal microscope for non-invasive imaging of human cancer in small animal models (Fall 08)